Wilms Tumor and Kidney Cancer  

In 2017, Margaret Anne Palmer was diagnosed with Wilms Tumor, a form of kidney cancer most commonly found in children. Her tumor was discovered by chance. When Margaret Anne was a baby, she had clogged tear ducts, which made her eyes look like they had pink eye. Doctors said they would place stents when she turned one to open the ducts. 
On the day of the procedure, while she was in recovery, the family received a call from the doctors saying they were keeping her longer to monitor her blood pressure. After learning about this, her pediatrician, Kelly McMIllian, MD, referred her to a nephrologist.

The following day, the nephrologist’s office called to say two doctors had reviewed her case. When they arrived at the hospital, the radiologist told the family that they found a tumor on Margaret Anne’s right kidney and needed to do a CT scan to see if the cancer had spread. It had not. Margaret Anne underwent surgery for a total nephrectomy at Children’s of Alabama, performed by Elizabeth Beierle, MD. 

“We were fortunate that the tumor hadn’t spread, and she didn’t require chemotherapy or radiation,” added Natalie. “Margaret Anne had follow-up scans every three months, and then, after three years, the frequency was reduced to every six months.

 But in July 2022, during a routine four-year oncology follow-up with Kimberly Whelan, MD,, the radiologist once again came in with shocking news. She’d found another tumor, about the size of a golf ball, on her left kidney. This time, it was considered a second primary cancer, and Margaret Anne’s treatment would be more intensive. 

Within the week, she had a port placed, and chemotherapy began to shrink the tumor, which she named “Wilma.” She started kindergarten during this time, and despite the challenges, her spirit remained strong. After several rounds of chemotherapy, the tumor had shrunk enough for surgery. In September 2022, the surgeon removed part of her left kidney. 

“The tumor had been very close to a critical artery, and we were grateful that it was successfully removed. Margaret Anne lost much of her hair, and we had to make the difficult decision to shave her head,” said Natalie. “But with incredible courage, she stood up in front of her kindergarten class to explain why she had done it.”

Margaret Anne’s experience at Children’s was beyond incredible. Dr Beierle was so confident and compassionate about how she was going to approach each surgery. “As a mom and a nurse, my mind was racing with all of the worst possible thoughts. She took time and walked us through all options as well as providing us with the comfort that she had our child's best interest as her priority too,” explained Natalie. “Dr. Whelan was also very thoughtful during the second diagnosis and let us know that despite Margaret Anne’s situation being unusual, she would make sure to consult with all of her colleagues to ensure we had the best plan moving forward.”

Natalie added that Children’s has such an incredible outreach to the patients and families by providing healthcare, support and even the fun activities to help children have something to look forward to during their hospital stay. “I can’t imagine how our lives would have been impacted if we would not have had the privilege of Children’s so close and available. Margaret Anne has had the ability to participate in so many activities affiliated with Children’s of Alabama including Smile-A-Mile and UA Miracle Kids supporting Children’s Miracle Network Hospital.”

Despite everything she’s been through, Margaret Anne continues to shine. She loves cheerleading, tumbling, swimming, and spending time with her friends. The bigger the challenge, the more determined she becomes. She even enjoys reminding her older brother that she’s tough and can handle anything.

“Margaret Anne is a strong, resilient girl who clearly has a bigger purpose,” added Natalie. “She continues to inspire those around her, and we’re so grateful to be part of such a wonderful community that provides hope and support to families facing similar challenges.” She hopes to one day cheer for the University of Alabama and become a healthcare professional to help other people.